ACMG Announces Upcoming CEO Transition in 2025

The American College of Medical Genetics and Genomics (ACMG) announced that Melanie Wells, MPH, CAE, Chief Executive Officer of ACMG and the ACMG Foundation for Genetic and Genomic Medicine (ACMGF), will step down from her role, concluding her tenure on November 21, 2025. Wells will continue to support the organizations through the transition period, and ACMG and ACMGF will appoint an interim CEO shortly to ensure continuity of leadership and operations.

Wells joined the organizations in 2016 and has served in multiple leadership capacities, including Director of Administration, Chief Operating Officer, and, most recently, CEO. During her tenure, she led ACMG and ACMGF through significant operational transformation and financial stabilization, ensuring both organizations are primed with strength and positioned for growth.

ACMG President Mira Irons, MD, FACMG, expressed gratitude for Wells' leadership and the lasting impact of her tenure:

"Melanie has led ACMG and the ACMG Foundation through a period of remarkable progress and transformation. Her dedication, steady leadership, and strategic focus have positioned both organizations for continued growth and success. On behalf of the Board, I thank Melanie for her years of service and the strong foundation she leaves for the next chapter in ACMG's evolution."

ACMGF President Nancy Mendelson, MD, FACMG, also reflected on Wells' partnership and lasting contributions to the Foundation:

"Melanie's leadership strengthened the vital connection between the College and the Foundation and expanded the Foundation's capacity to support education, innovation, and philanthropy in medical genetics. Her vision and commitment have set both organizations on a path of stability and growth, and we are deeply grateful for her service."